Barnes & Noble takes over the vacant retail space formerly home to a Duane Reade | Upper East Site, Ajay Suresh (inset) Barnes & Noble Plans New Upper East Side Bookstore after Two Year Absence by Upper East Site Staff November 15, 2022, 12:38 pm 3 Comments Barnes & Noble is coming back to the Upper East Side in a big way after a two year absence, announcing plans on Tuesday to open a new bookstore — with a much smaller footprint — just over a block away from the original location along the busyAlready a subscriber? Log in here. Continue reading with an Upper East Site subscription. Read More Comments are closed. 3 Comments Expand All Collapse All Sort by Newest Oldest What a wonderful decision for B&N to return to the UES. We must do everything possible to support all of our bookstores on the UES. This makes me so incredibly happy. It was such a shame when the big B&N closed on E86th Street. 100%!